Reverse triiodothyronine

Clinical information

The biologically active metabolite reverse triiodothyronine (rT3) is created during impaired conversion of tetraiodothyronine (T4) to triiodothyronine (T3).


Low T3 syndrome (euthyroid sick syndrome, non-thyroidal illness) is characterised by a disturbed homeostasis of thyroid hormones. This results in an accumulation of the inactive metabolite rT3, a normal to low TSH level, a low FT3 level and, with a long disease duration, a low FT4 level. The determination of rT3 can be useful to differentiate between patients with central hypothyroidism and patients with low T3 syndrome.

Selected Products

ELISAreverse triiodothyronine (RT3)antibody-coated
microplate wells